Lentivirus (LVs) are single stranded RNA (sRNA) viruses, which are a subgroup of the retrovirus family. They can integrate into the host genome in both dividing and non-dividing cells, with a wide range of cell, resulting in long-term expression both in vitro and in vivo. The delivery vehicles based on HIV-1 have been developed by BrainVTA.
How do I obtain virus packaging services?
● You can click
Pre-Made LVs to find out whether the list contains what you need.
● Also, You can obtain custom-Made LVs service by clicking
here.
Characteristics of (HIV) Based Vectors
● Infects dividing and non-dividing cells;
● Long term, stable gene expression resulting from genomic integration;
● Pseudotyping with a VSV-G envelope glycoproteins that broaden cell tropism;
● Factors such as expression cassette size or choice of envelope will influence titer;
● HIV accommodates insert sizes of 6.5 kb. Larger expression cassettes can be packaged but decreases in titers will be expected.
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Further information about the lentiviral vectors, just click the
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